BCL-XL (Ab-62) Antibody MBS9403603 from MyBioSource.com

Description

Potent inhibitor of cell death. Isoform Bcl-X(L) anti-apoptotic activity is inhibited by association with SIVA isoform 1. Inhibits activation of caspases By similarity. Appears to regulate cell death by blocking the voltage-dependent anion channnel (VDAC) by binding to it and preventing the release of the caspase activator, cytochrome c, from the mitochondrial membrane. The Bcl-X(S) isoform promotes apoptosis

Product Specs
ItemBCL-XL (Ab-62) Antibody
CompanyMyBioSource.com
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberMBS9403603
Quantity0.025 ml
ApplicationsWestern Blot (WB)
Concentration1.0 mg/ml
Conjugate/TagUnconjugated
FormatSupplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
PurityAntibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide
ReactivityHuman, Mouse, Rat
TargetBCL-XL
Molecular Weight25,290 Da
HostRabbit
ImmunogenThe antibody detects endogenous level of total BCL-XL protein
NCBI Full Gene NameBCL2-like 1
NCBI Gene AliasesBCLXS, BCL-XL/S, PPP1R52, bcl-xS, Bcl-X, BCLX, bcl-xL, BCL2L, BCLXL
ClonalityPolyclonal